Dendritic cell (DC) vaccines have recently emerged as an innovative therapeutic option for glioblastoma patients.To identify novel surrogates of anti-tumor immune responsiveness, we studied the dynamic expression of activation and inhibitory markers on peripheral blood lymphocyte (PBL) subsets in glioblastoma patients treated with DC vaccination at
Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog
A 5-year-old spayed female German shepherd dog was admitted with a history of generalized stiffness.Neurologic examination revealed mild paraparesis with multifocal spinal pain.Spinal radiographs and magnetic resonance imaging revealed diskospondylitis at L6-7 and multiple sites throughout the thoracolumbar spine.Biopsy of the intervertebral disk a